Ref: IRC129093
Salary is from £29,155 per annum inclusive of London Allowance.

Division of Mycobacterial Research                                                                            
Cellular mechanisms of immunity to Mycobacterium tuberculosis

Situated in Mill Hill, North West London, NIMR is the largest MRC institute, supporting some 70 research groups and 500 bench scientists. The Institute provides excellent training for researchers in a multi-disciplinary environment and is equipped with state of the art facilities. http://www.nimr.mrc.ac.uk/employment/

A 2-year postdoctoral position is available in the laboratory of Maximiliano Gutierrez at the MRC National Institute of Medical Research.

Our group is interested in the area of cellular microbiology of M. tuberculosis with a particular focus on the innate immune system and phagocytosis. In particular, we are interested in understanding how M. tuberculosis survive within host cells and the mechanisms that host cells use to eliminate intracellular M. tuberculosis. The proposed project aims to investigate the role of the host factor LRRK-2 in immunity to Mycobacterium tuberculosis.

A high level of self-motivation and the ability to work in an international team are essential for this position. Substantial knowledge in image acquisition/processing/analysis (including FRAP/FRET) and cell culture techniques is an advantage. The project is embedded within a dedicated mycobacterial research group with interests in the interaction between M. tuberculosis and host cells. Opportunities for internal and external collaboration are available.

To join us you’ll need:

• A PhD degree (or be in the final stages of completion) in cell biology, biochemistry, microbiology or related area.
• Independence, high motivation and good communication skills.
• Proven experience with advance microbiological and cell biology techniques as well as in containment level 3 (Biosecurity level 3) with M. tuberculosis.

In return for your talents, we offer a competitive salary, 30 days annual leave on appointment, a final salary pension scheme and flexible working hours.