美国波士顿儿童医院泌尿学博士后职位

POSTDOCTORAL POSITION – DEPARTMENT OF UROLOGY -CHILDREN'S HOSPITAL BOSTON/HARVARD MEDICAL SCHOOL

A postdoctoral position is open in the Lee laboratory, located at the Proteomics Center and Department of Urology at Children's Hospital Boston / Harvard Medical School. The Lee lab works closely in conjunction with the Hanno Steen lab and the Proteomics Center at Children’s Hospital Boston. In addition it is part of the Urologic Diseases Research Center / NIH George M. O’Brien Urology Center at Children’s Hospital Boston / Harvard Medical School. Our lab is interrogating the urinary proteome to identify novel and clinically relevant markers of urologic disease, in particular renal damage, urinary tract infection, and bladder dysfunction. Projects for this position will specifically focus on interrogating specific urinary proteins identified as potential biomarkers of renal damage and determining their biologic significance and relationship to renal injury. Candidates will be responsible for various aspects of proteomics and biochemical experiments from sample preparation to data analysis. These projects will require experience in molecular biology, and / or mass spectrometry and protein modifications. An additional interest in glycobiology or glycoproteomics is preferred, but not necessary. Working knowledge of LC-­‐ESI-­‐MS/MS and HPLC operation is preferred. Experience with analysis of large data sets and bioinformatic tools are preferred.