Postdoctoral candidate (Microbiology - Cell biology) : London, United Kingdom 

We are seeking a postdoctoral-level researcher to apply for a Marie Curie Individual Fellowship to work on MRSA pathogenesis.

Description

Our objective is to dissect the interaction of Methicillin-Resistant Staphylococcus aureus (MRSA) with mammalian host cells. We have recently discovered that the depletion of a human membrane protein called TMEM59 results in the reduced intracellular replication of MRSA, while host cell viability remains unaffected (EMBO J, 2013. 32(4):566-82). The candidate will perform a range of genomic, proteomic and metabolic profiling studies to find previously unknown factors required for the intracellular survival of MRSA. This could lead to the identification of novel host-targeted therapeutics against MRSA, which may circumvent the problem of antibiotic resistance. The successful applicant will join the Health Sciences Research Centre (HSRC) at the University of Roehampton. The HSRC represents a multidisciplinary team with research interests on different aspects of human disease, ranging from neurological disorders, to bacterial infections or metabolic disorders. 84% of our research output is rated as internationally excellent and world leading in terms of originality, significance and rigour (REF2014). The HSRC has well-equipped laboratories including an ultra-high performance liquid chromatography triple quadrupole mass spectrometer (UPLC-(TQ)-MS), clinical and microscopy analysers, molecular biology equipment, and cell and tissue culture facilities. Our excellent research facilities make the HSRC a stimulating environment for postdoctoral researchers.

Benefits

The grant provides an allowance to cover your living, travel and family costs. The grant is awarded to your host organisation, usually a university, research centre or a company in Europe. The research costs and overheads of the host organisation(s) are also supported.