美国哈佛大学医学院病毒蛋白质工程博士后职位

Postdoctoral Fellow in Viral Protein Engineering : Boston, MA, United States

A Postdoctoral Fellow in Protein Engineering, Synthetic Virology, and Structure-Function Analysis is available in the Grousbeck Gene Therapy Center at Mass Eye and Ear and Harvard Medical School.

The Grousbeck Gene Therapy Center is a multidisciplinary team of investigators pursuing the study of host-vector interactions, the development of enabling gene therapy technologies, and the translation of preclinical therapeutic gene transfer programs. The Center groups a multi-disciplinary team of scientists, labs, and core facilities that provide a dynamic and intellectually stimulating environment on a mission to study and develop treatments for diseases of unmet need. Our work sits on the crossroads of Synthetic Biology, Virology, Immunology, and Molecular Medicine for which we seek motivated and talented scientists to participate in our research.

We are now seeking highly talented inpiduals that are passionate about protein engineering and structure-function studies on complex multimeric protein assemblies such as viral capsids. We study the adeno-associated virus, one of the smallest mammalian viruses, and mainly known to be a potent vector for gene therapy, and seek to use next-generation approaches to interrogate the structure-function relationship relevant to its infectious biology. In turn, we aim to leverage these data toward more rational approaches of viral vector design for gene therapy applications.

We seek to complement our group with fellows that have a deep interest and background in protein design and engineering and a desire and skillset for bio-informatic analysis of large datasets. Beneficial, yet not required, is to have a relevant background in the fields of viral immunology, animal models, and/or AAV/virology.

Highly qualified candidates at a senior staff level can also be considered for this position.

Interested scientists with a PhD and/or MD and relevant background are considered. Compensation is commensurate with experience. Candidates should have a good proficiency of English, be able to work well in a team. Postdoctoral fellows will be able to enroll in a dedicated postdoctoral training program at Harvard Medical School.