美国威尔康奈尔医学院招聘癌症生物学方向博后

Postdoctoral Associate : New York, NY, NY, United States

The Englander Institute for Precision Medicine at Weill Cornell Medicine is seeking a highly-motivated postdoctoral researcher with a background in cancer biology or a related field to join our team.  We are seeking a dynamic individual who will be responsible for designing and executing studies focused on defining the functional impact of novel molecular alterations in cancer.

Our research is focused on the utilization of patient derived models of cancer, the definition of distinct molecular classes of cancer using genomic data from human samples, studying the functional impact of novel genetic and epigenetic alterations in preclinical models, and investigating the potential to translate these findings to clinical relevance. The work will be performed under the supervision of Dr. Himisha Beltran, Assistant Professor of Medicine, and Dr. Olivier Elemento, Associate Professor of and Director, Englander Institute for Precision Medicine. Our group is heavily involved in next generation sequencing of human cancers, including large-scale collaborative efforts such as TCGA and SU2C/PCF Dream Team. The candidate will work within an integrated, multidisciplinary team composed of basic scientists, computational biologists, pathologists, and medical oncologists, with significant resources for bioinformatics support and studies in human tissues.
The candidate is expected to perform experiments exploring high-throughput drug screening platforms, organoid model development, tumor microenvironment, tumor metabolism, and genetic and epigenetic alterations using a variety of preclinical model systems including cell lines, xenografts, and genetically engineered mouse models. A desire to develop and implement new methodologies is highly advantageous. There will be numerous opportunities for training to complement current skills, and we envision numerous collaborations with other outstanding scientists.
Applicants should have completed a PhD in a related field, together with a strong publication record, and strong previous research experience in signal transduction, transcriptional control, genomics and bioinformatics, or related fields. Experience with several of the following activities would be desirable: characterization of genetically engineered mouse models, work with patient-derived xenografts and culture of primary cells. Initial salary is commensurate with experience. Applying for independent funding is not required, but is strongly encouraged for the career development of the candidate.