瑞典卡罗林斯卡医学院免疫生物学博士后职位

Description of research group and project
The project will be of an interdisciplinary nature, and use primarily biophysical methods to answer immunological questions about Natural Killer (NK) cells. NK cells are lymphocytes involved in the innate immune system. The project will be lead by Ph D Sofia Johansson, who has focused her research on the interactions between NK cell receptors and their ligands. The postdoc will take part in a bigger constellation of researchers within cellular immunology, which is well renowned and leading within basic research on Natural Killer (NK) cells. The methods used will primarily be advanced fluorescence-based biophysical methods to study protein dynamics and protein-protein interactions. These may include high resolution imaging (in particular Stimulated Emission by Depletion) and/or fluorescence-based dynamic methods, such as Fluorescence Correlation Spectroscopy (FCS). Traditional immunological techniques like flow cytometry and cytotoxicity assays can also be used. For the biophysical aspects, a collaboration is established with Experimental Biomolecular Physics at the Royal Institute of Technology. For more information, look at the Johansson group’s home page, http://ki.se/ki/jsp/polopoly.jsp?d=23387&a=132789&l=en.

Duties and responsibilities
The goal will be to address molecular aspects of NK cell biology. The postdoc will together with S. Johansson formulate a project plan based on the postdoc’s expertise and knowledge. The postdoc is expected to run his or her own projects, and also to take part in collaborations with research colleagues. The postdoc should be able to independently plan, conduct and analyze experiments with fluorescence-based methods such as FCS and high resolution microscopy. Immunological and molecular biology techniques may also be used. Evaluation of the results and discussions together with the supervisor and other colleagues is an important part of the work, so good social and communication skills are required. The admitted candidate should also be prepared to take his or her share of common duties in the lab. The candidate should furthermore be able to present his or her results in scientific articles, as well as orally in an international scientific context.

Eligibility/Qualifications
The postdoc should be interested in pursuing an interdisciplinary project, involving quantitative biophysical as well as traditional immunological methods. The admitted candidate must have a doctoral degree in either cell biology/immunology or similar field with experience of biophysical techniques, or a degree in biophysics/biotechnology or similar with experience of cellular work. The admitted candidate must be fluent in English, written and orally. We are looking for a highly motivated person with a desire to advance science, both by intellectual contributions and by performing experiments. The admitted candidate should have self-drive, be curious, and be capable of working both individually and in a team.

Highly qualifying merits:
- Theoretical and practical knowledge of fluorescence based biophysical techniques (e.g. fluorescence correlation techniques, fluorescence lifetime, FRET).
- Scientific excellence proven by at least one publication in a journal of good scientific standard.
- University level mathematics, mathematically skilled.
- Experience of programming, especially in Matlab.
- Analytical skills, confirmed contributions to scientific publications.

Qualifying merits:
- Theoretical and practical knowledge in cellular and immunological techniques (e.g. flow cytometry, cytotoxicity assays, confocal imaging).
- Experience of molecular biology techniques.
- Good writing and oral presentation techniques.
- Knowledge of biomedically relevant statistics.

Entry requirements
Scholarships to pursue postdoctoral studies may be awarded to individuals who come from other countries with the intention of remaining in Sweden only while obtaining all or part of their education. The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish PhD or higher. Having received a salary or other remuneration from Karolinska Institutet during the past two years may be disqualifying.

One requirement for receiving a scholarship for postdoctoral studies is central registration as a postdoc.

Type of scholarship
Karolinska Institutet awards scholarships to pursue postdoctoral studies. This educational scholarship, which is paid for a maximum of two years within seven years after the receipt of a PhD or the equivalent, is tax-exempt.

The amount is set for a maximum of six months at a time and is paid out on a monthly basis.

The position is for 1 year with the possibility of 1 year prolongation.

Application process
An application must contain the following documents in English:
1.Curriculum vitae and qualifications, presented in accordance with Karolinska Institutet’s qualifications portfolio (http://ki.se/meritportfolj )
2.A complete list of publications
3.A summary of current work and previous research experience(no more than one page)
4.Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances
5.Verification from the thesis defence committee or the equivalent (only if the thesis defence is scheduled within three months after the application deadline)

The application is to be submitted on the NetRecruiter system.