首都医学科学创新中心王立铭实验室招聘科研助理/博士后

首都医学科学创新中心（简称创新中心）是北京市新成立的具有独立法人资格的新型研发机构。创新中心以推动医学科学发展、改善人类健康为目标，开展生物医学研究，致力于提升医学科学创新与成果转化能力，提高疾病诊断和治疗水平。我们将汇聚世界高水平科学家及其科研团队，与首都医学教育和科学研究优质资源紧密合作，打造多学科交叉融合的科研平台，综合自由探索、医学目标导向、有组织科研等途径，实践新型科研模式和体制机制，逐步推进医教研产的深度融合，培养适应医学科学创新发展的优秀人才。

一、实验室介绍

王立铭，首都医科大学公共卫生学院院长、博士生导师，首都医学科学创新中心资深研究员、人类遗传与分子医学研究所所长。实验室长期关注机体代谢的神经生物学调控机理研究。在Nature、Nature Neuro science、PNAS、eLife、Cell Research等知名期刊发表多篇研究论文。同时致力于大众科学传播和教育，出版专著《吃货的生物学修养》、《上帝的手术刀》、《生命是什么》、《笑到最后》、《给忙碌者的病毒科学》等科普书籍，发行量超30万册，先后获得国家图书馆“文津图书奖”，科技部全国优秀科普作品，“吴大猷科普著作奖”等奖励。

二、实验室研究方向

包括人类在内，动物的生存和健康很大程度上依赖于对机体能量和必须营养物质水平的精确调节和维持，而中枢神经系统在这方面发挥了不可或缺的重要功能。通过实时的感知机体内部的能量和营养物质储备，以及环境中食物的分布，中枢神经系统可以通过精密的行为调节，保证动物机体的代谢平衡。而一旦这一调控机制被破坏，将可能引发包括进食障碍、肥胖症在内的一系列神经和代谢系统疾病。

实验室对神经系统与代谢系统相关联的生物学问题有广泛的兴趣。近期的研究工作将主要利用定量行为分析、活体钙成像、遗传筛选和分析、单细胞转录组和环路追踪等技术，在果蝇和小鼠模型中研究如下两个相互独立但互相关联的生物学问题：

l 神经系统如何参与机体能量和重要营养物质代谢的调控

l 动物各器官如何协同参与机体代谢的调控和代谢病的发生

三、代表性文章

Elife. 2023 Sep 12;12:e85365. PMID: 37698486

Cell Res. 2023 Jun;33(6):434-447. PMID: 37055592

Cell Res. 2021 May;31(5):580-588. PMID: 33273704

Elife. 2020 Apr 23;9:e53103. PMID: 32324135

Cell Res. 2018 Oct;28(10):1013-1025. PMID: 30209352

Cell Discov. 2018 Dec 4;4:66. PMID: 30534416

四、岗位信息

01、科研助理

1）主要职责

1.在导师及合作导师共同指导下参与实验室的课题研究；

2.协助处理实验室公共事务。

2）任职要求

1.获得生物学/基础医学相关领域本科或硕士学位，毕业时间一般不超过三年；

2.有实验室学习经历者优先；

3.对科研工作充满热情和自我驱动力、对代谢和代谢相关疾病有强烈兴趣、有团队合作精神。

02、博士后

1）主要职责

1.在导师及合作导师共同指导下参与实验室的课题研究；

2.协助处理实验室公共事务。

2）任职要求

1.获得生物学/基础医学相关领域博士学位，毕业时间一般不超过三年；

2.在生物学/基础医学相关领域有第一作者论文发表；

3.对科研工作充满热情和自我驱动力、对代谢和代谢相关疾病有强烈兴趣、有团队合作精神。

五、福利待遇

1.根据应聘者的工作经验和能力，提供具有市场竞争力的薪酬（详情面谈）；

2.享受五险一金、带薪年假、体检和补充医疗保险等；

3.支持个人职业发展，提供必要的工作相关专业培训。

六、申请方法

凡符合招聘岗位要求且有意向者，请准备申请材料：

1.个人简历

2.学术成果及奖励清单

发邮件至songtingting_ext@cimrbj.ac.cn

邮件主题按照“博士后应聘+姓名+博士后招收网”或者“研究助理应聘+姓名”的格式标注，初审合格后会发出面试通知。

联系人：宋老师

联系地址：北京市丰台区右安门外西头条10号-首都医学科学创新中心

本招聘长期有效，至招聘到合适人选为止。

ABOUT CIMR

The Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research. The CIMR is located at the main campus of the Capital Medical University, Beijing, China and committed to building a scientist-centered governance framework and fostering a diverse and inclusive work environment. For more information, please visit our website: www.cimrbj.ac.cn

Laboratory Introduction

Liming Wang is the Dean of the School of Public Health at Capital Medical University, a doctoral supervisor, a senior researcher at the Chinese Institutes for Medical Research in Beijing, and the director of the Institute of Human Genetics and Molecular Medicine. His laboratory has long focused on studying the neural and biological regulatory mechanisms of metabolism in the body. He has published numerous research papers in prestigious journals, including Nature, Nature Neuroscience, PNAS, eLife, and Cell Research. Additionally, he is dedicated to science communication and education, having authored popular science books such as Biological Cultivation of Foodies, God's Scalpel, What Is Life, Laughing Until the End, and Virus Science for Busy People, which have collectively sold over 300,000 copies. He has received several prestigious awards, including the Wenjin Book Award from the National Library, the National Excellent Science and Technology Popularization Works Award, and the Wu Daohu Science Popularization Book Award.

Major Research Projects

The survival and health of animals, including humans, largely depend on the precise regulation and maintenance of energy and essential nutrient levels in the body. The central nervous system plays an indispensable role in this process. By continuously monitoring the internal energy and nutrient reserves of the body, as well as the availability of food in the environment, the central nervous system can maintain metabolic balance through precise behavioral regulation. However, when this regulatory mechanism is disrupted, it can result in a range of neurological and metabolic disorders, including eating disorders and obesity.

Our laboratory has a diverse array of interests concerning the biological issues related to the nervous and metabolic systems. Our recent research will concentrate on employing quantitative behavioral analysis, in vivo calcium imaging, genetic screening and analysis, single-cell transcriptomics, and circuit tracking to explore two distinct yet interconnected biological questions in Drosophila and mouse models:

How does the nervous system regulate energy metabolism and the utilization of essential nutrients?

How do animal organs synergistically participate in the regulation of metabolism and the development of metabolic diseases?

Representative Publications

Elife. 2023 Sep 12;12:e85365. PMID: 37698486

Cell Res. 2023 Jun;33(6):434-447. PMID: 37055592

Cell Res. 2021 May;31(5):580-588. PMID: 33273704

Elife. 2020 Apr 23;9:e53103. PMID: 32324135

Cell Res. 2018 Oct;28(10):1013-1025. PMID: 30209352

Cell Discov. 2018 Dec 4;4:66. PMID: 30534416

Open Positions

Research Assistant

Main Responsibilities

a. Counducting research project under the guidance of the supervisor and the co-supervisor.

b. Getting involved in laboratory public affairs.

Qualifications

a. A bachelor's degree or a master's degree in biology or a related field of basic medicine, typically completed within three years after graduation.

b. A laboratory learning experience is preferred.

c. Be passionate and self-motivated in scientific research, possess a strong interest in metabolism and metabolic-related diseases, and demonstrate the ability to work collaboratively as a team player.

Postdoctoral Researcher

Main Responsibilities

a. Counducting research project under the guidance of the supervisor and the co-supervisor.

b. Getting involved in laboratory public affairs.

Qualifications

a. A doctoral degree in a related field of biology or basic medicine, typically completed within three years of graduation.

b. First-author papers published in the fields of biology and basic medicine.

c. Be passionate and self-driven in scientific research, possess a strong interest in metabolism and metabolic-related diseases, and demonstrate the ability to work effectively as a team player.

Welfare Treatment

a.Offering a competitive salary that is commensurate with the candidate's work experience and skills, as assessed during a comprehensive interview.

b. Enjoying five types of insurance, a single fund, paid annual leave, a physical examination, and supplementary medical insurance, among other benefits.

c.Supporting personal career development and providing necessary job related professional training.

How to apply

For individuals who meet the qualifications for the recruitment position and are interested, please prepare the necessary application materials:

a. Personal resume

b. List of Academic Achievements and Awards

Please send an email to

songtingting_ext@cimrbj.ac.cn

The subject line of the email should follow the format "Name + postdoc application or Name + research assistant", and an interview notice will be issued following the preliminary examination.

Contact person: Tingting Song

This recruitment is valid for the long term until a suitable candidate is recruited.

原文出处：

https://mp.weixin.qq.com/s/ilVCvJ0jI7DGg9iX5AtBgA